EXPLORE TRNA WITH 4SR BIOSCIENCES
A new frontier
WHO WE ARE
How We Got Here
We are a start up from the University of Chicago. Cofounders, Prof. Tao Pan and Chris Katanski, created 4SR to expand upon Prof. Pan's decades of research into the biology and functional genomics of tRNA. We are pushing NextGen sequencing to study the complex biology of tRNA in a variety of spaces, ranging from cancer early detection to microbiome.
Multiplexed sequencing from small RNA
We have developed a approach to generate libraries for NextGen sequencing focused on capturing the biology of tRNA. Our approach captures tRNA abundance, modifications, fragments, and amino-acylation, all in a single sequencing run. Our approached is has been optimized to accommodate RNA from challenging clinical samples including tissue, biofluids, nasal swabs, and more. With this technology we can begin to ask new questions about tRNA biology.